Personalized Medicine

This is a patient-centric module with three options for medicine recommendation.

In Datasets, "subTCGA vs. CMap (all mutation)" is short for mutation pattern matched TCGA vs. CMap, and "subTCGA vs. CMap (specific mutation)" is short for mutation pattern matched TCGA vs. CMap (cell line specific mutation).

Search by matched cell line according to the similarity between their mutation profiles.

    
Export:
Datasets Cancer
Type		 Cell Line Compound Dosage Time Number of
Reversed Gene		 Number of
Adverse Gene		 RADE
TCGA vs. CMap PRAD PC3 BRD-A03772856 500 nM 6 h 374 10 0.100 Detail Download
TCGA vs. CMap PRAD PC3 BRD-A03772856 1 µM 6 h 498 29 0.163 Detail Download
TCGA vs. CMap PRAD PC3 BRD-A03772856 10 µM 6 h 408 16 0.134 Detail Download
TCGA vs. CMap PRAD PC3 BRD-A03772856 3 µM 6 h 384 4 0.037 Detail Download
TCGA vs. CMap PRAD PC3 trichostatin-a 500 nM 6 h 537 32 0.155 Detail Download
TCGA vs. CMap PRAD PC3 trichostatin-a 1 µM 6 h 541 29 0.138 Detail Download
TCGA vs. CMap PRAD PC3 trichostatin-a 10 µM 6 h 545 31 0.146 Detail Download
TCGA vs. CMap PRAD PC3 trichostatin-a 3 µM 6 h 584 39 0.160 Detail Download
TCGA vs. CMap PRAD PC3 geldanamycin 500 nM 6 h 290 2 0.033 Detail Download
TCGA vs. CMap PRAD PC3 geldanamycin 1 µM 6 h 330 2 0.025 Detail Download
Showing 1 to 10 of 376486 entries
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Select key mutation gene.

Sample Group Effect Type Effect Result
With mutation Reversed
Gene Fold change of cancer samples vs. normal samples Fold change of compound treated vs. DMSO treated cell lines
Adverse
Gene Fold change of cancer samples vs. normal samples Fold change of compound treated vs. DMSO treated cell lines
Without mutation Reversed
Gene Fold change of cancer samples vs. normal samples Fold change of compound treated vs. DMSO treated cell lines
Adverse
Gene Fold change of cancer samples vs. normal samples Fold change of compound treated vs. DMSO treated cell lines

Upload users' file (official symbols of genes having mutations).