Compound Detail

Differential gene expression analyses have been performed on both cancer vs. control tissues samples (E1) from TCGA and molecular compound treated cell line vs. DMSO treated cell line (E2) from the CMap database.
When a cell line is treated with a compound, if the effect on a gene is opposite, i.e., one up-regulated or 1 in E1 and the other down-regulated or -1 in E2, or conversely, we consider it having a reversed effect on this gene. Otherwise, if a gene is marked as 1(E1) ~1(E2), -1(E1) ~-1(E2), 0(E1) ~1(E2) or 0(E1) ~-1(E2) with 0 for no change, we consider that the compound has an adverse effect on this gene.

trichostatin-a

ID: BRD-A19037878 | Dosage: 1 µM | Time: 6 h

Genes Fold change of
cancer samples vs. normal samples 		Fold change of
compound treated vs. DMSO treated cell lines
ABCG2 down -7.091 up 16.044
ABHD6 down -2.564 up 29.671
ACAN up 2.286 down -5.061
ACOT11 down -2.268 up 5.109
ACSF2 down -2.713 up 9.639
ACSL6 down -32.703 up 5.286
ACSS3 down -2.319 up 4.543
ACTC1 down -5.897 up 7.399
ACTG2 down -3.174 up 8.883
ADGRG6 down -2.458 up 3.89
ADGRV1 up 2.147 down -2.919
ADH1B down -3.095 up 5.851
ADM2 up 2.445 down -4.53
ADRA2B down -2.707 up 8.132
ADRB1 up 2.071 down -3.099
AGMAT up 2.408 down -5.142
AGTR1 up 2.666 down -2.377
AJAP1 down -2.963 up 3.767
AKR1B1 down -14.798 up 6.928
ALDH1A3 up 2.044 down -8.126
ALOX15 up 3.443 down -7.363
AMACR up 9.505 down -5.151
ANGPT1 down -4.18 up 5.264
ANK2 down -2.596 up 6.185
ANXA2P2 down -2.658 up 2.604
ANXA6 down -2.24 up 8.58
ANXA9 down -3.037 up 4.139
AOC3 down -2.13 up 5.835
AOX1 down -5.345 up 17.302
APOB down -2.494 up 3.998
APOBR down -2.243 up 3.76
ARC down -7.025 up 11.791
ARHGEF28 down -2.095 up 3.253
ARHGEF40 down -2.754 up 4.614
ARL4D down -3.486 up 5.701
ARMCX1 down -2.342 up 4.547
ASB9 up 2.319 down -12.011
ASF1B up 2.275 down -11.937
ASPM up 2.616 down -9.897
ASPN up 3.519 down -3.491
ASS1 down -2.329 up 5.634
ASTN1 down -3.999 up 8.041
ATOH1 up 14.971 down -2.378
ATP1A2 down -3.073 up 2.937
ATP1B1 down -2.213 up 26.261
ATP2A3 down -2.251 up 10.019
ATP2B4 down -2.741 up 7.677
ATP6V0A4 down -5.576 up 7.171
ATP8A2 up 11.657 down -3.802
AURKB up 2.903 down -33.076
AVPI1 down -2.224 up 10.476
B3GALT2 down -2.829 up 9.307
B3GNT4 up 2.022 down -3.13
BAIAP2L2 up 4.689 down -4.813
BCAM up 2.029 down -2.78
BCL2 down -2.077 up 3.802
BDNF down -2.431 up 5.655
BGN up 2.011 down -2.327
BICD1 up 2.975 down -11.043
BIRC5 up 3.842 down -10.3
BMP5 down -4.571 up 8.193
BMP6 up 2.391 down -3.076
BOP1 up 2.362 down -6.138
BUB1 up 2.573 down -11.415
BUB1B up 2.785 down -3.226
C14orf132 down -2.463 up 14.817
C16orf45 down -2.356 up 3.401
C21orf62 down -5.628 up 10.649
C4orf19 down -2.494 up 5.624
C7 down -2.279 up 8.587
CA2 down -22.205 up 5.256
CA4 down -3.52 up 5.678
CACNA1D up 4.459 down -2.608
CALD1 down -2.436 up 5.741
CAMK1D down -2.032 up 6.715
CAMKK2 up 3.176 down -18.573
CAP2 down -2.139 up 2.95
CAPG down -2.324 up 5.942
CAPN6 down -4.558 up 2.206
CASC5 up 2.045 down -2.878
CAV2 down -2.638 up 10.578
CAV3 down -2.223 up 7.693
CBLC up 2.293 down -6.952
CBR3 up 2.125 down -11.913
CBX8 up 2.144 down -3.934
CCDC181 down -2.409 up 6.944
CCDC69 down -2.568 up 12.755
CCK down -3.591 up 8.266
CCL11 up 2.044 down -2.84
CCL17 up 2.246 down -3.465
CCL18 up 3.907 down -3.683
CCNA2 up 2.478 down -18.013
CCNB2 up 2.39 down -17.222
CDC25C up 3.537 down -5.311
CDC42EP3 down -2.201 up 2.416
CDC45 up 2.585 down -6.541
CDCA3 up 2.387 down -14.191
CDCA8 up 2.396 down -6.229
CDH22 down -2.091 up 4.221
CDH7 up 2.153 down -6.464
CDK18 down -3.385 up 3.269
CDK5R1 up 2.238 down -3.247
CDO1 down -4.862 up 7.491
CEND1 down -2.868 up 10.045
CENPA up 3.755 down -6.535
CENPF up 2.966 down -12.643
CENPM up 3.182 down -2.32
CENPN up 2.519 down -18.953
CEP55 up 2.489 down -3.095
CERK down -2.329 up 4.108
CHIT1 up 4.328 down -8.767
CHRNA1 up 2.49 down -2.51
CHRNA5 up 2.075 down -6.698
CHST11 down -2.354 up 5.749
CLCA4 down -5.663 up 5.136
CLIC4 down -2.039 up 10.579
CLIP3 down -2.687 up 5.093
CLSTN2 down -2.052 up 7.33
CLU down -6.008 up 5.7
CNTN1 down -2.424 up 2.194
COL10A1 up 4.775 down -3.898
COL21A1 down -2.448 up 8.123
COL9A1 down -2.366 up 5.16
COMP up 4.469 down -5.541
CORO2B down -2.551 up 2.307
CPED1 down -2.572 up 5.863
CPNE6 down -4.555 up 7.964
CRABP1 down -4.091 up 3.169
CRTAC1 down -19.791 up 8.147
CRYBA2 up 3.08 down -2.823
CSRP1 down -2.737 up 8.063
CST6 down -3.889 up 4.106
CTF1 down -2.396 up 4.725
CXCL14 up 2.346 down -5.915
CXCR2 down -6.188 up 2.809
CYP11A1 down -3.19 up 6.983
CYP26B1 down -3.72 up 5.34
CYP2E1 down -3.585 up 8.791
CYP2W1 down -2.416 up 7.041
CYP3A5 down -4.019 up 7.245
CYP4B1 down -4.508 up 4.063
DAAM2 down -3.244 up 10.872
DCN down -2.041 up 9.946
DCSTAMP up 3.052 down -3.15
DDIT4 down -2.291 up 13.578
DDR2 down -2.293 up 10.051
DEFB1 down -2.284 up 5.006
DGCR9 up 3.654 down -3.755
DIAPH3 up 2.023 down -2.125
DIXDC1 down -2.078 up 7.42
DKK3 down -2.066 up 13.686
DLGAP5 up 3.082 down -18.33
DMBT1 down -4.804 up 8.61
DMD down -2.942 up 2.143
DNAJB1 down -2.269 up 11.454
DNAJB4 down -2.421 up 18.868
DNAJC15 down -2.454 up 2.148
DOK4 down -2.143 up 2.574
DPP6 down -4.648 up 3.246
DPYS down -2.65 up 2.721
DRD2 down -3.01 up 4.049
DTNA down -2.51 up 12.414
DUOX1 down -4.436 up 3.622
DUOX2 down -6.065 up 4.465
DUS1L up 2.121 down -9.688
DUSP2 down -5.265 up 6.721
DUSP5 down -2.049 up 13.597
EBF2 up 4.787 down -2.042
EDIL3 down -2.289 up 6.755
EDN3 down -3.244 up 16.51
EDNRA down -2.492 up 7.94
EDNRB down -2.994 up 21.37
EFCAB1 down -2.016 up 2.641
EFEMP1 down -2.582 up 4.925
EFHD1 down -2.38 up 13.796
EFNB1 down -2.434 up 8.861
ELAVL2 up 4.871 down -3.481
ELAVL3 down -2.626 up 13.321
EN2 up 5.967 down -4.088
EPCAM up 2.156 down -17.13
EPHB1 down -4.249 up 4.666
ERCC6L up 2.257 down -9.213
ESPL1 up 2.483 down -3.754
ESRP2 up 2.204 down -7.593
ETNK2 down -2.388 up 8.424
ETV5 down -2.138 up 12.692
EXO1 up 2.473 down -8.028
EYA1 down -2.343 up 6.464
EYA4 down -3.284 up 3.891
F12 up 3.812 down -6.015
FAM107A down -3.006 up 6.172
FAM64A up 2.906 down -15.357
FASN up 2.622 down -8.701
FAT4 down -2.253 up 8.496
FAXDC2 down -2.667 up 14.179
FCGBP down -3.891 up 4.246
FCGR3B down -3.268 up 2.756
FERMT2 down -2.509 up 4.266
FEV up 3.896 down -7.926
FFAR2 up 3.452 down -15.714
FGF2 down -2.231 up 5.261
FGF7 down -2.718 up 3.785
FHL1 down -2.814 up 11.162
FLRT3 down -2.456 up 11.532
FN1 down -3.23 up 6.778
FOLH1B up 3.73 down -5.045
FOXD1 up 11.748 down -7.161
FOXF1 down -2.117 up 10.645
FOXF2 down -2.243 up 5.127
FOXL2 up 5.186 down -3.87
FOXM1 up 2.832 down -15.252
FSCN2 up 2.054 down -2.273
FXYD6 down -3.097 up 5.251
FZD8 up 2.854 down -7.649
G0S2 down -4.894 up 3.492
GAD1 up 2.262 down -6.035
GAL up 5.298 down -8.028
GALNT6 down -2.213 up 5.071
GAS1 down -2.365 up 8.499
GATM down -2.688 up 8.61
GCNT3 down -2.667 up 3.447
GHRHR up 3.267 down -2.304
GJA1 down -2.464 up 7.54
GNAL down -2.69 up 6.717
GNAO1 down -5.666 up 9.591
GNAZ down -3.468 up 15.08
GNG11 down -2.05 up 4.94
GOLM1 up 3.394 down -5.639
GPD1 down -5.293 up 10.398
GPM6A down -3.135 up 9.042
GPRASP1 down -2.141 up 6.149
GPX3 down -2.147 up 10.893
GRM4 up 2.445 down -5.965
GSTM1 down -10.276 up 5.394
GSTM2 down -2.366 up 9.014
GSTM3 down -4.911 up 7.601
GSTM4 down -2.297 up 2.911
GSTP1 down -4.174 up 5.728
GTSE1 up 3.823 down -18.493
HAAO down -2.07 up 2.512
HAND2 down -2.175 up 2.857
HAPLN2 down -2.008 up 3.244
HEPH down -2.339 up 5.097
HEY2 up 2.215 down -2.269
HIF3A down -2.956 up 7.494
HIST1H2BN up 2.205 down -2.947
HJURP up 4.179 down -10.254
HLF down -2.26 up 4.353
HMMR up 2.654 down -10.709
HOXC6 up 7.748 down -4.575
HPD down -2.811 up 5.279
HPN up 5.672 down -7.209
HR down -2.099 up 2.499
HRH2 down -2.616 up 5.231
HSD11B1 down -2.571 up 13.904
HSD17B2 down -2.135 up 6.475
HSF4 up 3 down -8.977
HSPA1A down -2.031 up 8.439
HSPA4L down -2.691 up 8.299
HSPA6 down -11.835 up 11.534
HUNK down -2.442 up 3.701
ID3 down -2.335 up 6.098
ID4 down -3.099 up 3.071
IER3 down -3.242 up 12.098
IGF2BP2 down -2.052 up 2.94
IL1RL1 down -4.471 up 7.706
IL33 down -2.155 up 14.453
IL5RA up 3.678 down -2.034
INSM1 up 3.068 down -2.769
IQSEC3 down -2.707 up 9.64
IRX4 up 2.39 down -13.582
ITGA8 down -2.039 up 8.597
ITGB3 down -2.709 up 9.698
ITGBL1 up 2.995 down -5.623
ITIH5 down -2.304 up 11.831
JAKMIP2 down -2.283 up 14.39
KAT2A up 2.026 down -18.355
KCNAB1 down -2.876 up 3.723
KCNJ5 down -8.76 up 6.636
KCNJ8 down -2.293 up 4.428
KCNK3 down -2.143 up 3.452
KCNMB2 up 2.613 down -2.306
KCNQ1 down -3.739 up 8.897
KIAA0101 up 2.064 down -4.712
KIAA1644 down -2.677 up 4.085
KIF14 up 2.605 down -4.437
KIF18B up 3.877 down -12.192
KIF20A up 2.927 down -15.69
KIF26B down -2.846 up 5.323
KIF4A up 3.416 down -8.231
KIFC1 up 2.651 down -15.322
KLK12 up 5.564 down -3.972
KLK14 up 4.47 down -4.991
KRT23 down -3.172 up 2.582
KRT4 down -4.422 up 6.431
L1CAM down -2.405 up 11.971
LARGE down -2.276 up 7.741
LDB3 down -3.125 up 2.888
LGALS4 down -3.287 up 10.675
LIMS2 down -2.208 up 13.966
LINC00115 up 2.295 down -5.49
LIPC down -3.557 up 2.843
LIPG down -7.103 up 7.601
LMOD1 down -3.082 up 3.157
LRMP down -2.332 up 2.594
LRP1B down -3.172 up 3.984
LRRC17 down -2.293 up 4.245
LRRC31 up 2.24 down -7.353
LRRN3 down -2.838 up 12.147
LSAMP down -2.57 up 16.029
LYVE1 down -4.831 up 6.301
MAMLD1 down -2.93 up 2.327
MAP1A down -2.882 up 15.129
MAP1B down -2.31 up 4.046
MASP1 down -2.625 up 11.938
MATK up 5.983 down -10.721
MBNL2 down -2.089 up 18.963
MCAM down -2.096 up 9.459
MCCC2 up 2.393 down -13.675
MCM10 up 2.055 down -5.93
ME1 down -3.542 up 4.933
MEIS1 down -2.27 up 3.294
MELK up 3.051 down -6.452
METTL7A down -2.072 up 7.879
MKI67 up 2.849 down -7.726
MMP1 down -2.179 up 57.008
MMP26 up 8.47 down -10.514
MMP9 up 2.966 down -5.885
MNX1 up 4.631 down -6.818
MON1B up 2.942 down -6.466
MRPL12 up 2.05 down -5.274
MRPL41 up 2.435 down -5.403
MTG1 up 2.037 down -8.659
MXRA7 down -2.314 up 9.793
MYH3 down -2.159 up 8.954
NAV2 down -2.634 up 5.959
NCAM1 down -3.299 up 11.266
NCAPG up 3.312 down -12.578
NCAPH up 2.716 down -8.87
NDNF down -2.469 up 7.6
NDRG4 down -10.301 up 9.447
NEFM down -7.456 up 9.142
NEK2 up 3.063 down -3.346
NETO2 up 4.202 down -21.604
NFE2L3 up 2.076 down -3.415
NKX2-2 up 15.698 down -4.514
NLGN3 down -2.352 up 6.404
NME1 up 2.055 down -2.327
NPR2 down -2.07 up 7.443
NR4A3 down -2.395 up 11.402
NRCAM down -2.434 up 6.795
NRXN1 down -2.738 up 2.574
NSG1 down -3.033 up 13.126
NT5E down -2.429 up 3.212
NTRK1 down -2.225 up 6.055
NYNRIN down -3.769 up 3.356
OLFM4 down -4.046 up 7.693
OR51E2 up 5.291 down -2.56
ORC6 up 2.074 down -3.226
P2RX1 down -2.887 up 7.638
PALLD down -2.79 up 14.413
PBK up 2.835 down -11.339
PCDH9 down -2.384 up 2.637
PCDHB11 up 2.509 down -4.501
PCDHB3 up 2.124 down -7.75
PCSK6 up 3.061 down -5.878
PDK4 down -8.221 up 10.027
PDPN down -2.016 up 7.05
PEG10 down -2.098 up 8.598
PEG3 down -2.202 up 7.369
PENK down -4.494 up 6.441
PEX10 up 2.516 down -5.687
PFKFB3 down -2.11 up 4.343
PGF down -2.691 up 5.365
PIK3R1 down -2.003 up 2.976
PINLYP down -2.108 up 10.093
PIP5K1B down -3.397 up 9.41
PIPOX down -2.314 up 12.62
PLA2G2D up 2.474 down -5.831
PLA2G7 up 3.318 down -3.13
PLK1 up 2.702 down -24.159
PLP1 down -2.771 up 8.879
PNMA2 down -2.719 up 14.496
PNMT down -25.429 up 5.304
POLQ up 2.247 down -5.598
POU5F1B up 2.958 down -3.79
PPARGC1A down -3.37 up 2.75
PPEF1 up 2.315 down -6.213
PPP1R14B up 2.446 down -4.634
PPP1R3C down -3.14 up 8.838
PRKCA down -2.223 up 10.077
PRKCB down -3.439 up 10.723
PRKG1 down -2.99 up 4.199
PRODH down -2.59 up 5.343
PROM1 down -2.693 up 7.129
PRR16 up 3.583 down -10.355
PRR7 up 3.716 down -2.067
PRSS12 down -2.131 up 5.794
PTP4A3 up 2.779 down -2.648
PVT1 up 2.354 down -2.431
PYCR1 up 2.585 down -5.843
PYGL down -2.293 up 5.683
QPRT down -5.319 up 9.184
QSOX1 down -2.018 up 9.62
RAB26 up 2.415 down -3.126
RABEP2 up 2.121 down -10.445
RAD51 up 2.088 down -20.763
RASAL1 down -8.546 up 6.332
RBMS3 down -2.548 up 6.678
RBP1 down -2.764 up 20.777
RBP4 down -2.142 up 7.035
RBPMS down -2.098 up 6.01
REEP1 down -2.242 up 2.276
RELN up 3.249 down -2.022
RGN down -2.354 up 18.988
RGS11 up 3.354 down -10.565
RGS13 down -2.27 up 4.342
RGS9 down -2.384 up 4.054
RHCG down -4.043 up 10.762
RHOB down -2.075 up 9.838
RIMS3 down -2.375 up 9.239
RND2 down -2.758 up 17.594
RND3 down -2.315 up 3.776
ROBO1 down -2.201 up 4.847
RPE65 down -4.588 up 6.186
RRM2 up 4.032 down -9.964
RSPH14 down -2.926 up 3.495
S100A14 down -4.3 up 6.681
S100B down -2.473 up 3.968
SCARA3 down -3.363 up 6.829
SCGB1A1 down -5.573 up 9.355
SCN2B down -3.095 up 11.528
SCN5A down -3.402 up 5.194
SCRG1 down -2.308 up 2.625
SEC31B up 2.154 down -3.415
SELE down -2.159 up 6.932
SEMA3A down -3.135 up 10.509
SEMA3D down -2.155 up 2.607
SEMA5A down -2.166 up 11.074
SERPINA5 down -111.519 up 9.136
SERPINB1 down -2.22 up 3.403
SERPINB3 down -2.339 up 3.953
SFRP5 down -6.876 up 3.398
SFTPA2 up 4.066 down -2.808
SGCE down -2.085 up 14.283
SGK1 down -2.173 up 16.188
SHCBP1 up 2.687 down -13.019
SHOX2 up 2.243 down -2.519
SIK1 down -2.421 up 8.638
SIM2 up 4.714 down -10.705
SKA1 up 2.467 down -16.098
SLC14A1 down -3.751 up 10.015
SLC16A4 down -2.138 up 2.474
SLC16A7 down -2.017 up 6.122
SLC18A2 down -5.93 up 4.163
SLC19A1 up 2.722 down -26.22
SLC24A3 down -2.258 up 8.71
SLC25A10 up 2.212 down -6.249
SLC25A22 up 2.103 down -2.696
SLC26A3 down -26.536 up 8.144
SLC2A9 down -6.56 up 3.356
SLC4A10 up 2.043 down -3.296
SLC6A3 up 3.52 down -2.829
SLC7A11 up 3.074 down -17.53
SLC8A2 down -2.411 up 3.768
SLCO1A2 up 9.226 down -3.68
SLCO1B3 up 15.497 down -17.873
SLCO2A1 down -3.363 up 10.225
SLCO3A1 down -2.492 up 2.218
SLFN12 down -2.062 up 3.834
SMPDL3B up 3.23 down -6.291
SMTN down -2.304 up 3.324
SNAI2 down -2.87 up 5.071
SNCG down -3.109 up 3.801
SNHG3 up 3.009 down -4.452
SORBS1 down -2.891 up 2.811
SOSTDC1 down -3.713 up 3.018
SPAG5 up 2.261 down -9.956
SPC25 up 2.813 down -23.01
SPEG down -2.193 up 2.946
SPON1 down -3.019 up 6.912
SSPN down -2.127 up 2.299
SST down -3.852 up 12.268
SSTR1 up 4.107 down -4.034
SSTR2 down -2.342 up 2.656
ST5 down -2.257 up 8.801
ST6GALNAC4 down -3.498 up 5.448
STAC down -5.261 up 4.6
STIL up 2.211 down -5.332
SYCE1L up 3.497 down -2.638
SYNC down -2.474 up 4.986
SYNM down -3.472 up 7.813
TACC1 down -2.026 up 9.875
TAGLN down -2.549 up 10.156
TBX1 up 3.257 down -8.608
TBX4 down -4.529 up 3.829
TCEAL2 down -2.638 up 4.346
TDO2 up 4.344 down -5.435
TENM1 up 3.604 down -2.551
TENM3 down -2.323 up 9.663
TGFBR3 down -3.143 up 3.302
TGM1 down -2.493 up 2.895
THBS4 up 3.014 down -10.365
TIMP3 down -2.655 up 8.681
TINAGL1 down -2.295 up 6.203
TLR2 down -2.728 up 3.402
TMC5 up 2.315 down -2.054
TMEM100 down -3.594 up 7.171
TMEM158 down -2.159 up 4.121
TMEM35 down -3.796 up 2.051
TMOD1 down -2.061 up 15.994
TNN up 4.942 down -11.069
TNS1 down -2.71 up 7.71
TOP2A up 2.53 down -19.098
TPM1 down -2.684 up 3.627
TPX2 up 2.876 down -18.633
TRHDE down -3.201 up 2.543
TRIB3 up 2.035 down -22.137
TRIP13 up 2.313 down -27.045
TROAP up 3.545 down -8.596
TRPC4 down -2.236 up 6.77
TRPC6 down -2.787 up 3.245
TRPM2 up 2.684 down -4.095
TSPAN1 up 2.384 down -3.203
TTK up 2.302 down -17.276
TWIST1 up 4.473 down -5.691
TYRP1 up 2.721 down -4.404
UBE2C up 3.217 down -21.353
UNC5B down -4.668 up 7.793
VAX2 up 2.997 down -5.66
VCL down -2.616 up 4.017
VTN down -2.937 up 2.267
VWA5A down -2.347 up 9.109
WFDC1 down -2.272 up 8.927
WNT16 down -2.353 up 2.615
WWC3 down -2.626 up 10.582
YBX2 down -2.02 up 12.178
ZEB2 down -2.083 up 3.239
ZFPM2 down -2.197 up 6.875
ZNF185 down -4.044 up 3.705
ZNF692 up 2.173 down -10.055
Enrichment Result
GO
PID
KEGG
REACTOME
Pathway Name P-value Reverse Num Hit Num Gene List
Genes Fold change of
cancer samples vs. normal samples 		Fold change of
compound treated vs. DMSO treated cell lines
ADGRF5 up 2.386 up 15.821
ADORA2B down -2.039 down -23.818
AGT up 2.104 up 19.331
AHNAK2 down -3.358 down -16.405
ALDH3A1 down -2.898 down -23.898
APOBEC3C down -4.149 down -17.504
CHST3 down -2.175 down -16.754
CYP24A1 down -2.234 down -21.029
DUSP4 down -3.431 down -72.132
EDAR down -2.911 down -15.306
ETV1 up 2.341 up 17.387
FOSL1 down -3.064 down -95.184
GJB3 down -3.026 down -17.179
HIST1H1C up 2.121 up 17.66
HIST1H2AI up 2.789 up 18.872
HOXA7 down -2.359 down -19.62
HPCAL4 0 0 up 15.334
IFI6 up 2.815 up 23.761
IL11 up 2.548 up 19.265
ISG15 up 3.999 up 19.424
MECOM down -2.741 down -19.895
SDS up 2.776 up 20.411
SGSM3 0 0 up 16.456
SPINK2 0 0 up 15.917
TGFB1I1 down -2.414 down -16.146
TUBB2A up 2.595 up 20.774
TUBB4A up 7.899 up 17.762
ULBP2 up 2.895 up 25.604
VGF up 5.693 up 16.537
Enrichment Result
GO
PID
KEGG
REACTOME
Pathway Name P-value Adverse num Hit num Gene List

reverse gene
Genes Fold change of
cancer samples vs. normal samples 		Fold change of
compound treated vs. DMSO treated cell lines
adverse gene
Genes Fold change of
cancer samples vs. normal samples 		Fold change of
compound treated vs. DMSO treated cell lines