Compound Detail

Differential gene expression analyses have been performed on both cancer vs. control tissues samples (E1) from TCGA and molecular compound treated cell line vs. DMSO treated cell line (E2) from the CMap database.
When a cell line is treated with a compound, if the effect on a gene is opposite, i.e., one up-regulated or 1 in E1 and the other down-regulated or -1 in E2, or conversely, we consider it having a reversed effect on this gene. Otherwise, if a gene is marked as 1(E1) ~1(E2), -1(E1) ~-1(E2), 0(E1) ~1(E2) or 0(E1) ~-1(E2) with 0 for no change, we consider that the compound has an adverse effect on this gene.

trichostatin-a

ID: BRD-A19037878 | Dosage: 500 nM | Time: 6 h

Genes Fold change of
cancer samples vs. normal samples 		Fold change of
compound treated vs. DMSO treated cell lines
ABCC4 up 3.239 down -3.217
ABCG2 down -7.091 up 19.005
ABHD6 down -2.564 up 28.747
ABO down -2.498 up 4.588
ACAN up 2.286 down -3.461
ACE down -2.542 up 4.719
ACOT11 down -2.268 up 6.71
ACOX2 down -2.934 up 2.449
ACSF2 down -2.713 up 9.623
ACSL6 down -32.703 up 4.099
ACSS3 down -2.319 up 6.145
ACTC1 down -5.897 up 6.221
ACTG2 down -3.174 up 6.195
ADRA2B down -2.707 up 10.914
AGMAT up 2.408 down -3.514
AGTR1 up 2.666 down -4.668
AJAP1 down -2.963 up 3.688
AKR1B1 down -14.798 up 2.658
ALDH1A3 up 2.044 down -10.545
ALOX15 up 3.443 down -5.817
AMACR up 9.505 down -2.984
ANGPT1 down -4.18 up 3.239
ANK2 down -2.596 up 7.539
ANXA2P2 down -2.658 up 3.107
ANXA6 down -2.24 up 8.28
ANXA9 down -3.037 up 5.342
AOC3 down -2.13 up 7.792
AOX1 down -5.345 up 17.262
APOB down -2.494 up 6.921
APOBEC3F down -2.145 up 3.865
APOBEC3G down -3.812 up 3.309
APOBR down -2.243 up 6.76
APOF up 5.369 down -2.008
AQP2 down -637.47 up 2.072
ARC down -7.025 up 9.408
ARHGEF26 up 3.1 down -2.425
ARHGEF28 down -2.095 up 3.941
ARHGEF40 down -2.754 up 4.11
ARL4D down -3.486 up 3.714
ARMCX1 down -2.342 up 3.945
ASB9 up 2.319 down -9.578
ASF1B up 2.275 down -6.701
ASPM up 2.616 down -7.772
ASS1 down -2.329 up 3.799
ASTN1 down -3.999 up 7.066
ATP1A2 down -3.073 up 2.59
ATP1B1 down -2.213 up 28.005
ATP2A3 down -2.251 up 13.479
ATP2B4 down -2.741 up 7.688
ATP6V0A4 down -5.576 up 6.914
ATP8A2 up 11.657 down -3.627
AURKB up 2.903 down -27.988
AVPI1 down -2.224 up 6.392
B3GALT2 down -2.829 up 8.836
BAIAP2L2 up 4.689 down -3.018
BCL2 down -2.077 up 2.072
BGN up 2.011 down -2.813
BICD1 up 2.975 down -11.033
BIRC5 up 3.842 down -9.102
BMP5 down -4.571 up 9.974
BMP6 up 2.391 down -4.569
BOP1 up 2.362 down -4.227
BUB1 up 2.573 down -9.85
C14orf132 down -2.463 up 11.269
C21orf62 down -5.628 up 9.676
C4orf19 down -2.494 up 2.911
C7 down -2.279 up 8.038
CA14 down -6.241 up 3.028
CA2 down -22.205 up 3.771
CA4 down -3.52 up 9.428
CALD1 down -2.436 up 6.728
CAMK1D down -2.032 up 9.313
CAMK1G down -2.499 up 2.309
CAMK4 down -2.013 up 4.463
CAMKK2 up 3.176 down -21.154
CAP2 down -2.139 up 5.892
CAPG down -2.324 up 3.957
CAPN6 down -4.558 up 3.519
CAV2 down -2.638 up 8.384
CAV3 down -2.223 up 7.724
CBLC up 2.293 down -5.353
CBR3 up 2.125 down -12.674
CBS up 2.468 down -2.471
CCDC181 down -2.409 up 7.066
CCDC69 down -2.568 up 14.62
CCK down -3.591 up 8.987
CCL17 up 2.246 down -2.297
CCL18 up 3.907 down -6.042
CCNA2 up 2.478 down -18.484
CCNB2 up 2.39 down -17.632
CCNJL down -2.508 up 5.982
CD200 down -2.294 up 3.162
CDC25C up 3.537 down -5.01
CDC42EP3 down -2.201 up 3.33
CDCA3 up 2.387 down -12.349
CDCA8 up 2.396 down -5.026
CDH22 down -2.091 up 4.184
CDH7 up 2.153 down -4.038
CDK18 down -3.385 up 10.051
CDK5R1 up 2.238 down -4.07
CDKL2 down -2.641 up 2.194
CDO1 down -4.862 up 7.252
CEACAM5 up 2.226 down -2.27
CELSR3 up 3.383 down -2.302
CEND1 down -2.868 up 10.909
CENPA up 3.755 down -5.536
CENPF up 2.966 down -10.182
CENPN up 2.519 down -18.065
CEP55 up 2.489 down -2.446
CERK down -2.329 up 3.446
CHD5 down -2.253 up 5.94
CHIT1 up 4.328 down -7.967
CHRD up 2.233 down -3.04
CHRNA5 up 2.075 down -7.861
CHST11 down -2.354 up 4.447
CLCA4 down -5.663 up 7.53
CLIC4 down -2.039 up 11.069
CLIP3 down -2.687 up 2.328
CLSTN2 down -2.052 up 5.458
CLU down -6.008 up 7.103
CNTFR down -3.365 up 3.729
COL21A1 down -2.448 up 6.858
COL9A1 down -2.366 up 7.746
COMP up 4.469 down -4.814
CPED1 down -2.572 up 5.709
CPNE6 down -4.555 up 6.911
CRABP1 down -4.091 up 3.657
CRTAC1 down -19.791 up 8.278
CRYAB down -2.683 up 2.307
CSRP1 down -2.737 up 6.718
CST6 down -3.889 up 5.316
CTF1 down -2.396 up 2.72
CXCL14 up 2.346 down -3.385
CYP11A1 down -3.19 up 9.032
CYP26B1 down -3.72 up 7.59
CYP27A1 down -2.083 up 2.182
CYP2E1 down -3.585 up 5.723
CYP2W1 down -2.416 up 9.071
CYP3A5 down -4.019 up 5.543
CYP4B1 down -4.508 up 3.563
DAAM2 down -3.244 up 9.18
DCN down -2.041 up 7.791
DDIT4 down -2.291 up 11.671
DDR2 down -2.293 up 9.65
DGKG down -2.652 up 2.859
DIXDC1 down -2.078 up 8.081
DKK3 down -2.066 up 11.42
DLGAP5 up 3.082 down -17.567
DMBT1 down -4.804 up 10.377
DNAJB1 down -2.269 up 9.543
DNAJB4 down -2.421 up 15.872
DOCK3 down -2.567 up 3.168
DOK4 down -2.143 up 3.797
DPP6 down -4.648 up 6.381
DPYS down -2.65 up 3.368
DRD2 down -3.01 up 5.877
DTNA down -2.51 up 11.094
DUOX1 down -4.436 up 4.188
DUS1L up 2.121 down -12.722
DUSP5 down -2.049 up 10.715
EDIL3 down -2.289 up 7.42
EDN3 down -3.244 up 20.742
EDNRA down -2.492 up 8.448
EDNRB down -2.994 up 17.408
EFCAB1 down -2.016 up 2.918
EFEMP1 down -2.582 up 3.828
EFHC2 down -2.181 up 3.095
EFHD1 down -2.38 up 14.342
EFNB1 down -2.434 up 8.528
EGLN3 down -2.159 up 4.508
ELAVL3 down -2.626 up 14.651
EN2 up 5.967 down -2.334
EPCAM up 2.156 down -8.593
EPHB1 down -4.249 up 6.364
ERCC6L up 2.257 down -8.185
ESPL1 up 2.483 down -2.516
ESRP2 up 2.204 down -8.402
ETNK2 down -2.388 up 8.645
ETV5 down -2.138 up 10.196
EXO1 up 2.473 down -5.587
EYA1 down -2.343 up 11.202
EYA4 down -3.284 up 7.975
EZH2 up 2.758 down -2.258
F12 up 3.812 down -8.288
FAM107A down -3.006 up 6.54
FAM64A up 2.906 down -14.637
FASN up 2.622 down -5.258
FAT4 down -2.253 up 8.856
FAXDC2 down -2.667 up 12.024
FCGBP down -3.891 up 3.316
FERMT2 down -2.509 up 4.852
FEV up 3.896 down -5.093
FFAR2 up 3.452 down -14.715
FGF7 down -2.718 up 3.605
FHL1 down -2.814 up 7.879
FLRT3 down -2.456 up 11.293
FN1 down -3.23 up 7.466
FOLH1B up 3.73 down -5.966
FOXD1 up 11.748 down -6.116
FOXF1 down -2.117 up 11.068
FOXF2 down -2.243 up 5.014
FOXL2 up 5.186 down -3.099
FOXM1 up 2.832 down -13.777
FXYD6 down -3.097 up 3.638
FZD8 up 2.854 down -3.248
G0S2 down -4.894 up 2.205
GAD1 up 2.262 down -6.707
GAL up 5.298 down -7.204
GALNT6 down -2.213 up 6.482
GAS1 down -2.365 up 5.225
GATM down -2.688 up 7.922
GCNT3 down -2.667 up 5.196
GFRA2 down -3.114 up 2.006
GIPC2 down -2.348 up 4.227
GJA1 down -2.464 up 10.073
GNAL down -2.69 up 7.046
GNAO1 down -5.666 up 11.599
GNAZ down -3.468 up 14.141
GNG11 down -2.05 up 2.07
GOLM1 up 3.394 down -4.037
GPD1 down -5.293 up 13.362
GPM6A down -3.135 up 7.211
GPM6B down -2.255 up 5.197
GPR161 down -2.374 up 3.876
GPRASP1 down -2.141 up 4.26
GPX3 down -2.147 up 11.028
GRM4 up 2.445 down -4.102
GSTM1 down -10.276 up 4.328
GSTM2 down -2.366 up 6.736
GSTM3 down -4.911 up 7.064
GSTM4 down -2.297 up 8.083
GSTP1 down -4.174 up 3.484
GTSE1 up 3.823 down -16.519
HAAO down -2.07 up 4.426
HAND2 down -2.175 up 6.19
HAPLN2 down -2.008 up 7.807
HECW1 down -2.545 up 3.633
HEPH down -2.339 up 4.832
HIF3A down -2.956 up 8.444
HJURP up 4.179 down -8.746
HLF down -2.26 up 4.864
HMMR up 2.654 down -10.692
HOXB3 down -3.076 up 2.299
HOXC6 up 7.748 down -8.383
HOXD13 down -3.449 up 2.415
HOXD3 down -2.756 up 5.023
HPD down -2.811 up 5.92
HPN up 5.672 down -6.946
HRH2 down -2.616 up 8.919
HSD11B1 down -2.571 up 11.415
HSD17B2 down -2.135 up 3.393
HSF4 up 3 down -2.845
HSPA1A down -2.031 up 8.074
HSPA4L down -2.691 up 9.804
HSPA6 down -11.835 up 10.153
HUNK down -2.442 up 4.944
ID3 down -2.335 up 5.283
ID4 down -3.099 up 3.974
IER3 down -3.242 up 11.873
IL1RL1 down -4.471 up 7.822
IL1RL2 down -2.431 up 3.042
IL33 down -2.155 up 11.738
IQCA1 down -2.536 up 2.22
IQSEC3 down -2.707 up 10.577
IRF5 down -2.625 up 5.13
IRX4 up 2.39 down -11.887
ITGA2 down -2.517 up 3.091
ITGA8 down -2.039 up 5.575
ITGA9 down -2.297 up 4.128
ITGB3 down -2.709 up 7.321
ITGBL1 up 2.995 down -10.496
ITIH5 down -2.304 up 11.565
JAKMIP2 down -2.283 up 11.893
JPH2 down -2.694 up 2.735
KAT2A up 2.026 down -18.537
KCNAB1 down -2.876 up 3.149
KCNB1 down -2.389 up 2.948
KCNJ5 down -8.76 up 10.237
KCNJ8 down -2.293 up 6.715
KCNK3 down -2.143 up 5.13
KCNN2 up 2.159 down -2.043
KCNQ1 down -3.739 up 8.012
KIAA0101 up 2.064 down -3.692
KIAA1644 down -2.677 up 4.491
KIF14 up 2.605 down -6.356
KIF18B up 3.877 down -11.268
KIF20A up 2.927 down -16.363
KIF26B down -2.846 up 7.329
KIF4A up 3.416 down -7.417
KIFC1 up 2.651 down -12.755
KRT16 down -5.347 up 2.082
KRT23 down -3.172 up 4.126
KRT4 down -4.422 up 8.61
L1CAM down -2.405 up 11.11
LARGE down -2.276 up 6.679
LDB3 down -3.125 up 4.79
LGALS4 down -3.287 up 10.081
LIMS2 down -2.208 up 7.544
LINC00115 up 2.295 down -3.985
LIPG down -7.103 up 8.37
LRP1B down -3.172 up 4.875
LRRC17 down -2.293 up 3.495
LRRC31 up 2.24 down -5.777
LRRN3 down -2.838 up 12.106
LSAMP down -2.57 up 15.527
LYVE1 down -4.831 up 3.248
MAMLD1 down -2.93 up 2.926
MAP1A down -2.882 up 12.963
MAP1B down -2.31 up 3.65
MASP1 down -2.625 up 14.471
MATK up 5.983 down -8.893
MBNL2 down -2.089 up 18.976
MCAM down -2.096 up 10.559
MCCC2 up 2.393 down -10.299
MCM10 up 2.055 down -4.374
ME1 down -3.542 up 4.676
MELK up 3.051 down -6.2
METTL7A down -2.072 up 9.31
MKI67 up 2.849 down -6.254
MMP1 down -2.179 up 48.179
MMP26 up 8.47 down -7.334
MMP9 up 2.966 down -3.658
MNX1 up 4.631 down -5.995
MON1B up 2.942 down -9.085
MPP6 up 2.317 down -3.832
MRPL12 up 2.05 down -3.597
MTG1 up 2.037 down -7.728
MXRA7 down -2.314 up 7.489
MYH3 down -2.159 up 8.012
MYL9 down -2.507 up 2.26
NAV2 down -2.634 up 2.999
NCAM1 down -3.299 up 13.585
NCAPG up 3.312 down -13.381
NCAPH up 2.716 down -8.164
NDNF down -2.469 up 8.025
NDRG4 down -10.301 up 8.235
NEFM down -7.456 up 7.641
NETO2 up 4.202 down -20.558
NKX2-2 up 15.698 down -4.298
NLGN3 down -2.352 up 6.688
NMUR1 down -2.514 up 4.938
NPR2 down -2.07 up 6.32
NR4A3 down -2.395 up 7.332
NRCAM down -2.434 up 12.336
NRXN1 down -2.738 up 5.331
NSG1 down -3.033 up 12.645
NTRK1 down -2.225 up 8.036
NUP210 up 2.35 down -2.368
NYNRIN down -3.769 up 4.362
OLFM4 down -4.046 up 10.486
ORC6 up 2.074 down -3.138
P2RX1 down -2.887 up 10.172
P2RX2 down -3.554 up 3.45
PALLD down -2.79 up 14.457
PARM1 down -2.154 up 3.536
PBK up 2.835 down -9.42
PCDH9 down -2.384 up 3.388
PDE7B down -3.187 up 4.565
PDK4 down -8.221 up 11.317
PDLIM5 up 3.023 down -2.579
PDPN down -2.016 up 6.285
PEG10 down -2.098 up 8.546
PEG3 down -2.202 up 8.414
PENK down -4.494 up 5.625
PEX10 up 2.516 down -5.039
PFKFB3 down -2.11 up 3.57
PGF down -2.691 up 11.02
PHYHIP down -2.441 up 6.413
PILRB up 2.36 down -2.512
PINLYP down -2.108 up 9.137
PIP5K1B down -3.397 up 10.248
PIPOX down -2.314 up 11.081
PLA2G2D up 2.474 down -2.773
PLA2G4A down -5.027 up 3.522
PLCL1 down -3.002 up 3.556
PLK1 up 2.702 down -20.527
PLP1 down -2.771 up 6.682
PNMA2 down -2.719 up 15.776
PNMT down -25.429 up 7.752
POLQ up 2.247 down -4.877
POPDC2 down -2.73 up 2.854
POU5F1B up 2.958 down -8.635
PPARGC1A down -3.37 up 2.751
PPEF1 up 2.315 down -2.958
PPP1R14B up 2.446 down -6.068
PPP1R3C down -3.14 up 11.063
PRDM8 down -3.128 up 2.68
PRKCA down -2.223 up 6.487
PRKCB down -3.439 up 12.484
PRKG1 down -2.99 up 6.678
PRLR down -3.418 up 2.551
PRODH down -2.59 up 4.506
PROM1 down -2.693 up 5.538
PRR16 up 3.583 down -12.442
PRSS12 down -2.131 up 7.273
PTGS1 down -5.671 up 2.206
PYCR1 up 2.585 down -4.521
PYGL down -2.293 up 4.368
QPRT down -5.319 up 6.503
QSOX1 down -2.018 up 8.918
RAB26 up 2.415 down -2.869
RABEP2 up 2.121 down -10.118
RAD51 up 2.088 down -17.633
RASAL1 down -8.546 up 7.895
RBMS3 down -2.548 up 6.724
RBP1 down -2.764 up 20.26
RBP4 down -2.142 up 7.306
REC8 down -2.032 up 2.972
REEP1 down -2.242 up 4.257
RGN down -2.354 up 18.568
RGS11 up 3.354 down -9.509
RGS13 down -2.27 up 3.63
RGS9 down -2.384 up 6.783
RHCG down -4.043 up 12.204
RHOB down -2.075 up 8.201
RIMS3 down -2.375 up 10.398
RNASE1 down -2.276 up 2.832
RND2 down -2.758 up 14.531
RND3 down -2.315 up 3.141
ROBO1 down -2.201 up 7.001
RPE65 down -4.588 up 7.758
RPL36A up 2.13 down -7.148
RRM2 up 4.032 down -8.516
RSPH14 down -2.926 up 4.343
S100A14 down -4.3 up 6.76
S100B down -2.473 up 5.053
SCARA3 down -3.363 up 2.53
SCGB1A1 down -5.573 up 7.895
SCN2B down -3.095 up 13.484
SCN5A down -3.402 up 4.592
SEC23A down -2.148 up 4.586
SEC31B up 2.154 down -2.655
SELE down -2.159 up 4.198
SEMA3A down -3.135 up 11.869
SEMA3D down -2.155 up 5.858
SEMA5A down -2.166 up 9.058
SERPINA5 down -111.519 up 13.911
SERPINB1 down -2.22 up 5.61
SFRP5 down -6.876 up 4.069
SGCA down -2.161 up 2.612
SGCE down -2.085 up 16.069
SGK1 down -2.173 up 11.493
SHCBP1 up 2.687 down -13.892
SIK1 down -2.421 up 5.098
SIM2 up 4.714 down -9.55
SKA1 up 2.467 down -15.042
SLC14A1 down -3.751 up 9.281
SLC16A7 down -2.017 up 2.616
SLC18A2 down -5.93 up 3.898
SLC19A1 up 2.722 down -23.212
SLC24A3 down -2.258 up 8.055
SLC25A10 up 2.212 down -3.174
SLC26A3 down -26.536 up 12.217
SLC2A9 down -6.56 up 4.801
SLC34A2 down -9.153 up 4.533
SLC43A1 up 2.882 down -4.486
SLC7A11 up 3.074 down -16.458
SLC7A5 down -3.351 up 2.779
SLC8A2 down -2.411 up 4.58
SLCO1B3 up 15.497 down -17.902
SLCO2A1 down -3.363 up 11.214
SLFN12 down -2.062 up 5.31
SMPDL3B up 3.23 down -5.106
SMS up 2.645 down -5.471
SNAI2 down -2.87 up 3.409
SNCG down -3.109 up 5.867
SNHG3 up 3.009 down -5.091
SOSTDC1 down -3.713 up 4.359
SPAG5 up 2.261 down -8.083
SPC25 up 2.813 down -18.015
SPEG down -2.193 up 2.077
SPOCK3 down -3.064 up 2.384
SPON1 down -3.019 up 6.64
SSPN down -2.127 up 2.254
SST down -3.852 up 13.31
SSTR2 down -2.342 up 6.413
ST5 down -2.257 up 4.192
ST6GALNAC4 down -3.498 up 5.776
STAC down -5.261 up 5.998
STARD8 down -2.331 up 2.456
STIL up 2.211 down -8.682
SYNC down -2.474 up 2.34
SYNM down -3.472 up 5.447
TACC1 down -2.026 up 10.468
TAGLN down -2.549 up 8.52
TBX1 up 3.257 down -4.774
TBX4 down -4.529 up 8.778
TCEAL2 down -2.638 up 5.445
TDO2 up 4.344 down -4.018
TENM3 down -2.323 up 10.035
TES down -2.215 up 2.083
TGM1 down -2.493 up 3.13
THBS4 up 3.014 down -7.951
TIMP3 down -2.655 up 9.771
TINAGL1 down -2.295 up 7.726
TLR2 down -2.728 up 5.619
TMC5 up 2.315 down -2.701
TMEM100 down -3.594 up 5.919
TMEM158 down -2.159 up 4.001
TMEM35 down -3.796 up 3.415
TMEM40 down -3.356 up 4.444
TMOD1 down -2.061 up 14.761
TNN up 4.942 down -8.933
TNS1 down -2.71 up 5.985
TOP2A up 2.53 down -19.234
TP53AIP1 down -2.689 up 2.869
TPM1 down -2.684 up 2.153
TPX2 up 2.876 down -14.358
TRHDE down -3.201 up 2.861
TRIB3 up 2.035 down -18.085
TRIP13 up 2.313 down -17.599
TRO down -2.165 up 3.348
TROAP up 3.545 down -6.996
TRPC4 down -2.236 up 4.437
TRPC6 down -2.787 up 4.135
TRPM2 up 2.684 down -2.177
TSPAN1 up 2.384 down -2.353
TTK up 2.302 down -15.947
TWIST1 up 4.473 down -2.095
TYRP1 up 2.721 down -6.028
UBE2C up 3.217 down -23.164
UNC5B down -4.668 up 7.08
VAX2 up 2.997 down -5.081
VCL down -2.616 up 2.161
VGLL1 down -2.912 up 3.289
VTN down -2.937 up 4.311
VWA5A down -2.347 up 9.966
WFDC1 down -2.272 up 9.045
WISP2 down -3.071 up 3.015
WNT16 down -2.353 up 4.297
WWC3 down -2.626 up 7.989
YBX2 down -2.02 up 14.863
ZFHX4 down -2.275 up 3.293
ZFPM2 down -2.197 up 6.276
ZNF185 down -4.044 up 2.469
ZNF536 down -2.865 up 3.126
ZNF692 up 2.173 down -8.194
Enrichment Result
GO
PID
KEGG
REACTOME
Pathway Name P-value Reverse Num Hit Num Gene List
Genes Fold change of
cancer samples vs. normal samples 		Fold change of
compound treated vs. DMSO treated cell lines
ADGRF5 up 2.386 up 17.602
ADORA2B down -2.039 down -21.465
AGT up 2.104 up 22.157
ALDH3A1 down -2.898 down -22.872
APOBEC3C down -4.149 down -16.124
CHST3 down -2.175 down -20.148
CYP24A1 down -2.234 down -19.043
DKK1 down -2.822 down -15.948
DUSP4 down -3.431 down -74.644
FOSL1 down -3.064 down -93.943
GJB3 down -3.026 down -17.46
GPX2 down -5.766 down -15
HIST1H1C up 2.121 up 16.741
HIST1H2AI up 2.789 up 17.262
HOXA7 down -2.359 down -16.25
HOXB7 down -5.896 down -17.611
HPCAL4 0 0 up 15.364
IFI6 up 2.815 up 23.226
IL11 up 2.548 up 16.224
ISG15 up 3.999 up 17.765
MECOM down -2.741 down -16.118
NCALD up 2.068 up 16.774
RGS10 up 2.219 up 17.01
SDS up 2.776 up 16.884
SGSM3 0 0 up 16.603
SYP up 2.024 up 15.007
TGFB1I1 down -2.414 down -20.851
TRIM29 down -3.022 down -17.299
TUBB2A up 2.595 up 18.398
TUBB4A up 7.899 up 19.893
ULBP2 up 2.895 up 22.544
VGF up 5.693 up 17.345
Enrichment Result
GO
PID
KEGG
REACTOME
Pathway Name P-value Adverse num Hit num Gene List

reverse gene
Genes Fold change of
cancer samples vs. normal samples 		Fold change of
compound treated vs. DMSO treated cell lines
adverse gene
Genes Fold change of
cancer samples vs. normal samples 		Fold change of
compound treated vs. DMSO treated cell lines